Product name : Magnolia Bark Extract
Latin Name : Magnolia officinalis L
Synonyms : Houpu, Houpu Magnolia, Magnolia
Active ingredients : Magnolol ,CAS Number : 528-43-8
Honokiol, CASNumber : 35354-74-6
Appearance: Light Yellow Brown fine powder
1 What is Magnolia bark extract?
Magnolia officinalis , commonly known as Houpu ,Hou Po, or Magnolia bark since the bark of the tree is the main active ingredient. It has been used for over 2,000 years as a herbal medicine in China .
The Magnolia bark, which is stripped from the stems, branches, and roots of Magnolia officinalis, contains magnolol and honokiol, two polyphenolic compounds that are commonly seen as the main active ingredients have demonstrated have anti-bacterial, anti- inflammatory , anti –depression, weight loss and other properties.
2 Magnolia bark extract benefits/effects
Magnolia bark extract has been used for centuries as a natural medicine to support a calm and positive mood, restful sleep and relaxation, memory, immunity, stress and weight management.
Fat loss : Magnolia Bark Extract has been added to weight loss supplements for the belief that it inhibits the production of the stress hormone cortisol which is thought to be responsible for the gain of body fat. The theory is that if cortisol can be blocked, it can lead to weight loss in those areas (particularly the midsection as cortisol is thought to affect those fat stores more than any others.) Magnolia Bark Extract also acts as a mild laxative
Asthma : Magnolol may stimulate corticosterone secretion by the adrenal gland, a mechanism similar to the action of exogenous glucocorticoids in the treatment of asthma
Anti-anxiety : Compared with diazepam (Valium), a well known pharmaceutical anxiolytic. Honokiol was found to be five times stronger than diazepam in reducing anxiety without the side effects of diazepam. While Diazepam does reduce anxiety, it also induces muscle relaxation, an effect not shared by honokiol. It would seem that honokiol is less likely than diazepam to induce physical dependence, central nervous system depression, motor nerve disruption, or amnesia at doses eliciting the anxiolytic effect. Because honokiol reduces anxiety without disruption of motor activity, it is postulated that the mechanism of the anxiolytic effect of honokiol is at least partially different from that of diazepam.
Alzheimers Disease : Magnolia has several powerful effects on acetylcholine levels in the brain, offering potential benefits for victims of Alzheimer’s Disease. Alzeimer’s Disease is characterised by insufficient levels of acetylcholine, accompanied by the buildup of amyloid plaque in the brain, disrupting normal brain functioning. Two biphenolic compounds found in Magnolia, Honokiol and magnolol, increase choline acetyltransferase activity, inhibit acetylcholinesterase, promote potassium-induced acetylcholine release and exhibit neurotrophic function in in vitro studies. Choline acetyltransferase is an enzyme involved in the cellular synthesis of acetylcholine, an increase of which can up-regulate the production of acetylcholine necessary for proper brain function. Acetylcholinesterase is an enzyme that breaks down acetylcholine, the inhibition of which preserves available acetylcholine. Honokiol and Magnolol also exhibited neurotropic effects in vitro, which could translate into enhanced brain cell growth and reduced brain cell death in vivo.
3 Magnolia bark extract Side Effects
No significant toxicity or adverse effects have been associated with traditional use of magnolia bark. However, it should not be taken together with beans because magnolia officinalis bark contains tannin while beans are rich in protein. These two ingredients would react and form non-digestible protein tannin. Also, it should be used with caution during pregnancy
Also , magnolia bark contains a substance called tubocurarine, which is an alkaloid that is commonly used as a muscle relaxant. The tubocurarine and related substances in magnolia bark may cause respiratory paralysis.
4 Magnolia bark extract recommended dosage
It is usually 200-400mg per day .
An exact dosage depends on person’s age, health, use purpose, materials content and other conditions, please consult your physician about the proper use