Sesame Seed Extract Sesamin
| Product name | Sesame Seed Extract Sesamin |
| Botanical Name | Sesamum indicum L. |
| Active ingredients | Sesamin(CAS NO : 607-80-7)
Sesamolin (CAS NO 526-07-8) |
| Appearance | White crystals or crystalline powder |
| Part used | Seed |
| Specification | Sesamin 10%–98% by HPLC
Sesamolin 10% ,20% ,50% by HPLC |
| Dosage | 750 mg –1500 mg per day |
| Main benefits | antioxidant , Antiviral activity, anti-inflammatory, weight loss |
| Applied industries | Nutrition Supplement, Medicine |
What is Sesame Seed?
Sesame seed is the seed of the sesame plant (Sesamum indicum L.). The plant is an annual herb with foxglove-like flowers that produce pods containing the edible sesame seeds. It is native to tropical areas in Asia, Africa, and South America.
Sesame seeds are rich in protein, vitamins, minerals, and antioxidants. They are commonly added to certain foods to provide a nutty flavor and crunchy texture.
Sesame seeds are also used as an ingredient in soap, cosmetics, lubricants, and medicines.
What is Sesame Seed Extract Sesamin
Sesamin (CAS NO: 607-80-7) is the most prominent lignan in sesame seeds. Sesamin is catered to be a nutritional supplement that confers antioxidant and anti-inflammatory effects.
Besides sesamin, the sesame seeds also have other lignans, including sesamolin (CAS NO 526-07-8), sesaminol and sesamol etc
How Sesame Seed Extract Sesamin works?
Sesamin appears to inhibit vitamin E metabolism, which causes a relative increase in circulating levels of γ-tocopherol and γ-tocotrienol; it shows most promise in augmenting the efficacy of vitamin E supplements. Science has revealed that sesamin supports liver and kidney health, positively stimulates cholesterol levels and posses potent antioxidant activity by increasing the absorption, use and recycling of vitamin E.
Sesame Seed Extract Sesamin benefits
Sesamin can be found from a plant extract called Sesamum indicum and Sesamin has numerous benefits for the body:
Sesamin and Antioxidant
As assessed by temporal ESR (a way to measure antioxidant effects in vivo using an injection of TEMPOL) 250 mg/kg Sesamin with 10 mg/kg vitamin E appears to increase reducing capacity of the liver (indicative of antioxidant effects) by 10-15% relative to control which is then normalized within one day following oral ingestion. (Anal Sci 2013, 29, 89.)
As sesamin can augment the efficacy of vitamin E, it may improve the antiaging process because of its antioxidant enzyme being active. And it may support skin health. Sesamin appears to augment the skin accumulation of γ-tocotrienol, and secondary to that increases its protective effects (J Nutr Sci Vitaminol 2008, 54, 117.). In short, Sesamin appears to augment the actions of all vitamin E vitamers simply because it allows more vitamin E to bioaccumulate in your body and exert their effects.
Sesamin and Weight Loss
According to a Japanese study, Sesamin does help break down fatty acids and may promote fat loss. It helps by decreasing the body’s capacity for storing fat. It may also help preserve lean muscle tissue and reduce fatty acids in the liver. This is why Sesamin is being used in numerous weight loss supplements.
In fact, sesamin could improve fat burning ability by boosting ketone production. Ketone production is seen in a lot of diet pill supplements as it produces the amino acids maintained by the body, supporting the body to spare muscle and target body fat for an energy source. It means that whilst you are dieting, your muscle mass will not lose, but your fat deposits will go down. It is what people who want to lose weight is looking for.
Sesamin lowers cholesterol
Sesamin can reduce LDL (bad cholesterol). Studies have shown that this plant lignan can help block absorption of cholesterol from the small intestine and lower activity of the enzyme HMG CoA reductase, which is involved in making cholesterol in the body. One study showed that 3.6 mg of sesamin lowered LDL by 16% and total cholesterol levels by 8% after two months.
Sesame Seed Extract Sesamin dosage
It appears that oral ingestion of around 100-300mg of Sesamin is sufficient to raise bodily sesamin stores to the level where it can preserve Vitamin E in the body. And someone recommend the range of 750 mg to 1500 mg prove to be most useful. So there has been limited human studies regarding the appropriate dosage of Sesamin.
Sesame Seed Extract Sesamin side effects
Very few side effects or negative effects of sesamin have been noted in scientific studies. Some experts have expressed concern that a high amount of sesamin is needed in order to reap some of its health benefits. Sesamin allergies have been reported, though they are rare.
